In August, Profiles in Science added an extensive selection from the papers of Sol Spiegelman, PhD (1914-1983), a pioneering molecular biologist whose discoveries helped reveal the mechanisms of gene action and laid the foundations of recombinant DNA technology.

“Sol Spiegelman was an extraordinarily creative scientist; his achievements include the first test-tube synthesis of an infective virus RNA and the development of RNA-DNA hybridization, an essential technique in molecular biology,” said Donald Lindberg, MD, director of the National Library of Medicine.

With the addition of the Spiegelman papers, the number of prominent researchers, public health officials, and promoters of medical research whose personal and professional records are presented on Profiles has grown to 23.